[10] the complications commonly including infertility and small, poorly functioning testicles (if present). 47,xxy (klinefelter syndrome) is a chromosomal variation in males where one extra x chromosome is present which then results in a 47,xxy The extra x chromosome typically affects physical, neurodevelopmental, behavioral and neurocognitive functioning. Klinefelter syndrome, also called 47,xxy, is a chromosomal condition that affects male development The signs and symptoms of klinefelter syndrome vary In some cases, the features are so mild that the condition is not diagnosed until puberty or adulthood
Researchers believe that up to 65 percent of people with klinefelter syndrome are never diagnosed A karyotype of 47,xxy may also be expected as mosaic with a 46,xy but the present case is rarely reported There have been studies reporting the low risk of malignancy in patients with the ovotesticular disorders. Longer cag repeats in androgen receptor gene correlate with severity. 47,xxy, commonly known as klinefelter syndrome, is a chromosomal condition that affects male development This genetic variation is characterized by the presence of an extra x chromosome in males, resulting in a 47,xxy karyotype instead of the typical 46,xy.
31 apparently, the prenatal incidence may be even higher, but abortive loss may be as high as 90% during the first trimester. It results from meiotic nondisjunction occurring during gametogenesis of the egg or sperm with subsequent fertilization of an xx ovum by a y bearing sperm, or fertilization of an x ovum by a sperm.
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